← Life Sciences DatabasesCONTENT HISTORYWHAT CHANGED · RULE-BASED ANALYSIS
Update to Life Sciences Databases
Snapshot Sep 30, 2026 · 23:01 UTC · version 0.1.5
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{
"name": "pharmgkb-skill",
"description": "Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search. Use when a user wants concise PharmGKB summaries",
"included_files": [
{
"relative_path": "scripts/rest_request.py",
"size_in_bytes": 1097
}
],
"skill_md_contents": "---\nname: pharmgkb-skill\ndescription: Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search. Use when a user wants concise PharmGKB summaries\n---\n\n## Source presentation\n<!-- source-presentation-contract:v2 -->\n- Add claim-adjacent links only for substantive claims supported by returned `sources`; never cite empty, metadata-only, or failed lookups.\n- Preserve `checked_sources`, use only supported `canonical_url` mappings, and leave requested raw or machine-readable output unchanged.\n- Use the `pharmgkb-skill` entry in `../../references/source-links.json` and follow `../../references/source-presentation.md`.\n\n## Operating rules\n- Use `scripts/rest_request.py` for all PharmGKB API calls.\n- Use the current `base_url=https://api.clinpgx.org/v1/data`; the former `api.pharmgkb.org` hostname was retired.\n- Single object lookups usually do not need `max_items`; list and search endpoints are better with `max_items=10`.\n- Re-run requests in long conversations instead of relying on older tool output.\n- Treat displayed `...` in tool previews as UI truncation, not literal request content.\n\n## Execution behavior\n- Return concise markdown summaries from the script JSON by default.\n- Prefer these paths: `gene/<id>`, `variant/<id>`, `clinicalAnnotation`, `dosingGuideline`, and search endpoints.\n- If the user needs the full payload, set `save_raw=true` and report the saved file path.\n\n## Input\n- Read one JSON object from stdin.\n- Required fields: `base_url`, `path`\n- Optional fields: `method`, `params`, `headers`, `json_body`, `form_body`, `record_path`, `response_format`, `max_items`, `max_depth`, `timeout_sec`, `save_raw`, `raw_output_path`\n- Common PharmGKB patterns:\n - `{\"base_url\":\"https://api.clinpgx.org/v1/data\",\"path\":\"gene/PA128\",\"max_items\":5}`\n - `{\"base_url\":\"https://api.clinpgx.org/v1/data\",\"path\":\"clinicalAnnotation\",\"params\":{\"relatedChemicals.accessionId\":\"PA449726\",\"limit\":10},\"max_items\":10}`\n - `{\"base_url\":\"https://api.clinpgx.org/v1/data\",\"path\":\"variant/PA166158545\",\"max_items\":5}`\n\n## Output\n- Success returns `ok`, `source`, `path`, `method`, `status_code`, `warnings`, and either compact `records` or a compact `summary`.\n- Use `raw_output_path` when `save_raw=true`.\n- Failure returns `ok=false` with `error.code` and `error.message`.\n\n## Execution\n```bash\necho '{\"base_url\":\"https://api.clinpgx.org/v1/data\",\"path\":\"gene/PA128\",\"max_items\":5}' | python scripts/rest_request.py\n```\n"
}SHA-256: 271c9861b5df1933a1168829fc043539a444d6aca321d97da250ab056341f789