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Update to Life Science Research

Snapshot Sep 30, 2026 · 23:18 UTC · version 1.0.3

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{
  "name": "pharmgkb-skill",
  "description": "Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search. Use when a user wants concise PharmGKB summaries",
  "included_files": [
    {
      "relative_path": "agents/openai.yaml",
      "size_in_bytes": 103
    },
    {
      "relative_path": "scripts/rest_request.py",
      "size_in_bytes": 10728
    }
  ],
  "skill_md_contents": "---\nname: pharmgkb-skill\ndescription: Submit compact PharmGKB API requests for genes, variants, clinical annotations, dosing guidelines, and search. Use when a user wants concise PharmGKB summaries\n---\n\n## Operating rules\n- Use `scripts/rest_request.py` for all PharmGKB API calls.\n- Use `base_url=https://api.pharmgkb.org/v1/data`.\n- Single object lookups usually do not need `max_items`; list and search endpoints are better with `max_items=10`.\n- Re-run requests in long conversations instead of relying on older tool output.\n- Treat displayed `...` in tool previews as UI truncation, not literal request content.\n\n## Execution behavior\n- Return concise markdown summaries from the script JSON by default.\n- Prefer these paths: `gene/<id>`, `variant/<id>`, `clinicalAnnotation`, `dosingGuideline`, and search endpoints.\n- If the user needs the full payload, set `save_raw=true` and report the saved file path.\n\n## Input\n- Read one JSON object from stdin.\n- Required fields: `base_url`, `path`\n- Optional fields: `method`, `params`, `headers`, `json_body`, `form_body`, `record_path`, `response_format`, `max_items`, `max_depth`, `timeout_sec`, `save_raw`, `raw_output_path`\n- Common PharmGKB patterns:\n  - `{\"base_url\":\"https://api.pharmgkb.org/v1/data\",\"path\":\"gene/PA36679\"}`\n  - `{\"base_url\":\"https://api.pharmgkb.org/v1/data\",\"path\":\"clinicalAnnotation\",\"params\":{\"relatedChemicals.accessionId\":\"PA449726\",\"limit\":10},\"max_items\":10}`\n  - `{\"base_url\":\"https://api.pharmgkb.org/v1/data\",\"path\":\"variant/PA166158545\"}`\n\n## Output\n- Success returns `ok`, `source`, `path`, `method`, `status_code`, `warnings`, and either compact `records` or a compact `summary`.\n- Use `raw_output_path` when `save_raw=true`.\n- Failure returns `ok=false` with `error.code` and `error.message`.\n\n## Execution\n```bash\necho '{\"base_url\":\"https://api.pharmgkb.org/v1/data\",\"path\":\"gene/PA36679\"}' | python scripts/rest_request.py\n```\n\n## References\n- No additional runtime references are required; keep the import package limited to this file and `scripts/rest_request.py`.\n"
}

SHA-256: 45ecfc282e83bea3eec1854df885d33b3f1545a17ec09bc15aa577b30ce42bd7